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hCG and Male Fertility

Let’s talk about hCG and male fertility.

hCG, male fertility. Upset woman is looking in pregnancy test. Frustrated man is sitting next to her.

As a treatment for low sperm count, hCG is surprisingly effective in a wide variety of situations.

The main benefit of hCG is that, generally speaking, it can restore fertility in men who suffer from a low sperm count, but it cannot help men who may have fertility issues due to erectile dysfunction, opioid dependence, or other issues.

hCG, or human chorionic gonadotropin, is one of many different infertility treatment options for men, but it tends to work best in men who suffer from secondary hypogonadism (hypogonadism is the medical term for low testosterone — secondary hypogonadism is a hormonal imbalance that centers in the pituitary gland or hypothalamus).

In our practice, hCG is sometimes used in conjunction with testosterone replacement therapy in an attempt to preserve or restore fertility — and, for men with low testosterone who still plan to have children, hCG monotherapy may be a good place to start, as hCG does have a limited capacity to induce testosterone production in the male body, in some cases, and may be sufficient on its own.

Testosterone replacement therapy (TRT) can often decrease the sperm count, which is the main reason that men who still plan on having children will hold off on testosterone-based therapy and opt for hCG monotherapy initially.

However, it’s more often the case that we combine hCG with several other drugs, including testosterone, to get testosterone levels back into a therapeutic range while still attempting to preserve some degree of fertility.

It is important to note that hCG is not guaranteed to preserve or restore fertility, however, it does seem that, based on the available scientific literature, your sperm count will return to normal after testosterone replacement therapy has been discontinued for several months.

hCG — Male Fertility Can Be Restored in Some Cases

Male fertility, discussed in this blog post on different types of fertility treatments, can be caused by a wide variety of factors. These factors include the following:

  • Low testosterone
  • An imbalance of other hormones
  • Sexually transmitted diseases
  • Erectile dysfunction
  • Psychological issues
  • Alcohol or drug use, abuse, or dependency
  • Genetic abnormalities like Klinefelter syndrome
  • Injury to the genitals
  • Undescended testicles
  • Low sperm count
  • Vasectomy
  • Varicocele

Because of the wide range of causes of male infertility, hCG is only one possible treatment, and it is not guaranteed to work in all cases. In fact, depending on the cause of your infertility, hCG, a male fertility treatment primarily indicated for men suffering from hormonally related infertility, may have no effect at all.

hCG — Male Fertility Generally Cannot Be Restored Through hCG Alone if the Patient Suffers From Physical or Psychological Blocks to Fertility

After treatment with hCG, male fertility can often be restored if the underlying cause of infertility is hormonally based. Unfortunately, it is not always the case that male infertility is being caused by a hormonal imbalance, as the list above indicates.

In fact, hCG as a male fertility restorative treatment is often only indicated in some cases of secondary hypogonadism.

Secondary hypogonadism is low testostosterone, or the imbalance of another hormone, caused by a problem with something other than your genitals, as opposed to primary hypogonadism, where there is some sort of testicular problem.

Basically, if your testes and penis work as they should, but your hormone levels are preventing you from producing sperm at levels required to get your partner pregnant, and this is combined with low testosterone, hCG may help to restore fertility while also partially or fully addressing your low testosterone levels.

That being said, if you suffer from damage to the testes, the inability to achieve or maintain an erection, drug or alcohol abuse or dependence, or psychological issues, hCG is not going to help — hCG merely helps your body to produce sperm the way it’s supposed to, and it cannot help with the physical components of sex.

Learn More About Testosterone Replacement Therapy, hCG, Male Fertility, and Treatment Options

To learn more about hCG, male fertility, testosterone replacement therapy, and your treatment options, click the button below.

Testosterone Replacement Therapy and Fertility



(Bill) William J. White, PA-C

(Bill) William J. White, PA-C brings over 20 years of surgical experience to our practice. He is a decorated veteran of the United States Army where he served for nearly 6 years with duty assignments, both here and abroad.   During his military career, Bill was trained as a Certified Surgical Technologist, and following an Honorable Discharge from the Army, he attended Texas Tech University.   He graduated with a Bachelor of Science in Biology and went on to attend PA School at the University of Texas Southwestern Medical Center at Dallas. He spent the first 10 years of his career in Neurosurgery.

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