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What Does Fatigue Mean? A Potential Sign of Disease

What does fatigue mean? The simple answer is feeling exhausted all the time — feeling so tired and unmotivated that you can’t do anything, day after day, week after week, month after month.

What does fatigue mean

This isn’t the same as simply feeling tired or exhausted. A hard day of physical or mental labor will leave anyone feeling exhausted. However, after a good night’s sleep, that should go away.

Fatigue is prolonged exhaustion. It often has two components — a mental side and a physical side. This means that you could very well be experiencing fatigue without necessarily feeling physically exhausted (or vice versa).

Here’s what it looks like, according to a report from the Journal of the Royal Society of Medicine:

  • Lack of motivation
  • Lack of alertness
  • Lack of energy
  • Lack of strength
  • Significantly affects your functioning
  • Isn’t proportionate to your exertion
  • Represents a clear change from a previous state

However, all of this is very subjective. Fatigue for one person might not be the same for the next.

So, What Does Fatigue Mean? It Can Mean Many Things, and That’s the Problem

The simple definition above isn’t as simple as you’d expect. How can you be sure that you lack strength regularly, for example, if you’re also exerting yourself so hard at work that you should lack strength? How can you be sure that the strength you lack is disproportionate?

It’s difficult to say, but we get into even murkier territory when we try to determine what fatigue actually represents medically.

You see, fatigue is probably one of the most common symptoms of illness. Hundreds of illnesses and disorders include fatigue as a symptom, including low testosterone and low estradiol.

What does fatigue mean alone? It’s hard to say. For example, it could mean low testosterone, or maybe it could mean depression, or Lyme Disease, or sleep apnea, or chronic fatigue syndrome — there’s no way to know without further testing.

And that’s really what chronic fatigue means — it’s a marker of disease. Something is wrong with your body if you’re constantly tired and unmotivated…

Usually. However, you may have other issues in your life that are causing these symptoms. If you only get 2 hours of sleep a night, you’re going to experience fatigue. If you’re constantly stressed at work, you’re going to experience fatigue. If you constantly go and never rest, you’re going to experience fatigue.

But, in the absence of outside stressors, if you’re experiencing fatigue, it may indicate a deeper issue.

So, what does fatigue mean? It means you should talk to your medical provider —‚if it’s been going on long enough that you’ve started searching the internet for answers, it’s time to see a professional.

Fatigue Should Be Investigated by a Professional

You need to see a medical care provider and find out what’s going on in your body — it’s not normal to be tired all the time.

Of course, it’s possible that your fatigue is related to low testosterone, whether you’re a man or a woman — this is actually fairly simple to rule out.

We provide a simple, $25 Low T Test and consultation to try to determine whether you’re suffering from a hormone issue — if we find that your hormones aren’t the problem, you can scratch one possible cause off the list.

Your blood test may even reveal what the actual cause is.

Click here to learn more about your free consultation and how to sign up for your $25 Low T Test.

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(Augie) Juan Augustine Galindo Jr. MPAS, PA-C

(Augie) Juan Augustine Galindo Jr. MPAS, PA-C started his career in healthcare as a fireman/paramedic in West Texas where he served on the Midland Fire Department from 1998-2004.   He became interested in testosterone treatment after seeing how hormone replacement doctors helped those suffering from low testosterone.   After graduating from the Texas Tech Health Sciences Center Physician Assistant Program, he moved to DFW where he currently lives with his wife and three children.


  1. Terry on 11/07/2016 at 1:05 pm

    My son, who is 36 yrs old, has learned that his testosterone level is 385. He has complained of being tired for months and low energy. He is very young to have this low of a level. Shouldn’t he look deeper to the root cause of why this is so low. I watched your youtube video 101 and learned that the pituitary and Hypothalmus regulate all this. Should he get some labwork to assess the function of these two organs.?
    thanks for your input

    • Augie Galindo on 11/22/2016 at 10:52 am


      He should definitely have more labs done to make sure there is no obvious evidence of hypothalamic/pituitary pathology, but unfortunately, it is no longer rare to see hypogonadism in men under the age of 40.

      Best regards,
      Augie Galindo MPAS, PA-C
      Testosterone Centers of Texas | Founding Partner

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