8 High Progesterone Symptoms in Women

I’ve written about the symptoms of low progesterone before, but high progesterone symptoms can be just as debilitating, both for women and for men. However, for the purposes of this article, I’m going to focus on high progesterone symptoms for women.

Doctor talking to woman about high progesterone symptoms

Now, while I can give you a list of symptoms (and I will), I want to speak a bit about one of the difficulties of diagnosing hormone issues — namely, that the symptoms of a particular hormone being high or low often look very similar to the symptoms of another hormone being high or low.

So while you might be experiencing high progesterone symptoms, you might also be experiencing high testosterone or estrogen symptoms and not know it.

So, while I’m going to give you a list of symptoms, I just want you to keep this in mind: The only way to be absolutely certain about the cause of your symptoms is to see a medical provider who specializes in hormone replacement therapy.

The reason this is so important is that hormone replacement therapy is a subtle science, and even with tests that show very clearly what your hormone levels are, it can still be hard to pinpoint the precise hormone causing the problem.

And this leads into another issue…

Hormones Don’t Act Alone

They act in concert, and many hormones are transformed from one type into another in various parts of your body.

They’re also different for everyone. While some baselines have been established for different hormones, everyone is unique, and what’s “high” for you may not be so for the next person.

Generally, hormone replacement therapy is not a simple matter of increasing a single hormone in your body and calling it a day. Instead, we try to find a balance of hormones that’s unique to your body, one that reduces your symptoms and lets you feel like yourself again.

Now that you have a clearer understanding of your hormones and how they work in your body, we can dive into the symptoms.

8 High Progesterone Symptoms

This is not a complete list, and you’re going to want to speak to your medical provider about any symptoms you might be experiencing.

The fact is, many of these symptoms can be indicative of other illnesses or disorders, so it’s important to have someone examine you who can get the entire picture.

  1. Low libido
  2. Depression
  3. Anxiety
  4. Mood swings
  5. Sudden weight gain
  6. UTIs (urinary tract infections)
  7. Fatigue
  8. Muscle weakness

As you can see, high progesterone symptoms run the gamut. They also look very similar to some of the symptoms of low testosterone and low estrogen.

The only way to know for sure if your progesterone levels are higher than they should be is to get your hormones checked.

This can often be done with a few simple tests. You’ll also want to explain your symptoms to your medical provider as best you can, just to ensure they have the clearest picture possible of what’s going on with you and your body.

If you want to talk to someone about the symptoms you’re experiencing, click the button to learn more about our free consultations.

See you soon.

Augie Galindo, PA-C

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(Augie) Juan Augustine Galindo Jr. MPAS, PA-C

(Augie) Juan Augustine Galindo Jr. MPAS, PA-C started his career in healthcare as a fireman/paramedic in West Texas where he served on the Midland Fire Department from 1998-2004.   He became interested in testosterone treatment after seeing how hormone replacement doctors helped those suffering from low testosterone.   After graduating from the Texas Tech Health Sciences Center Physician Assistant Program, he moved to DFW where he currently lives with his wife and three children.


  1. Lalita on 09/04/2020 at 10:21 am

    Sir progesterone affect my whole body
    Can I stop this Medicine during pregnancy

    • Hello Lalita,

      If you are already on progesterone, then it could be harmful to your pregnancy to stop taking it. Normal progesterone levels are important to a healthy pregnancy. Definitely speak to your obstetrician before making any changes in any hormones you might be taking.

      Best regards,
      Augie Galindo, PA-C
      Testosterone Centers of Texas | Managing Partner

  2. Mckenzie on 09/30/2020 at 3:08 pm

    Hello, what is the cause of high progesterone in women? I am trying to conceive and the first test I took earlier this year I was at 11.7 ng/ml and my most recent test is nearly double at 22.3 on a luteal phase scale of 2.6-21.5 ng/ml. Both tests were day 21 of my cycle. I definitely have a lot of the symptoms of high progesterone you have listed. How can I discover the root cause of my high progesterone? Thank you kindly.

    • Hello Mckenzie,

      Progesterone elevation (hyperprogesteronemia) is typically a cyclical issue, rather than a chronic over-production. So, it is seen clinically when there are elevations of progesterone in the early part of the menstrual cycle (follicular phase)and this can disrupt fertility and other hormonal processes. It may be helpful to see if the elevation is seen outside of the luteal phase. Your numbers are not far off the mark for day 21 readings, and should also be considered in light of your estradiol levels (i.e. P:E2 ratio). Looking at adrenal function and levels of precursor hormones may shed some light on the problem.

      Best regards,

      Augie Galindo, PA-C
      Testosterone Centers of Texas | Managing Partner

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