Your Thyroid and Low Testosterone — What’s the Connection?

Let’s discuss the relationship between men’s thyroid and low testosterone, particularly hypothyroidism and how testosterone replacement therapy could improve your health, feelings of wellbeing, and quality of life.

(It’s important to note that the symptoms of hypothyroidism differ between men and women — this article specifically addresses male hypothyroidism and Low T, but you can read more about hypothyroidism and low testosterone in women here.)

Thyroid and Low Testosterone — Some Basics

Taking a look at human anatomy for a moment, our thyroid gland is located just below your “Adam’s apple.” If you were to take a cross-section photograph of that area, you would find the larynx (voice box), the hyoid bone (often called the tongue bone), and the thyroid gland.

The thyroid is a butterfly shaped gland that is responsible for production of thyroid hormone.

female doctor touching the throat of a patient in the office — thyroid and low testosteroneWhen your thyroid doesn’t function properly, you either get too much thyroid hormone (a disease called hyperthyroidism), or too little thyroid hormone (a disease called hypothyroidism).

Areas often affected by fluctuations in thyroid hormone production are the skeleton, the heart, and the metabolic machinery of your cells.

Thyroid hormone (Triiodothyronine or T3) has regulatory effects on most organs of the body, and regulates our overall metabolic rate. That’s why it is connected to changes in body weight as well as changes in energy levels.

Learn More About Hypothyroidism Treatment for Men

Hypothyroidism and Testosterone Replacement Therapy — The Symptoms

The symptoms of low thyroid may include:

  1. Fatigue
  2. Low libido
  3. Erectile dysfunction (ED)
  4. Elevated cholesterol and weight gain
  5. Dry skin
  6. Inability to concentrate and remember
  7. Low blood pressure
  8. Thinning outer eyebrows
  9. Arrhythmias
  10. Feeling cold
  11. Constipation

It’s interesting to note that some of these symptoms overlap those we typically identify as symptoms of low testosterone, particularly the ones related to sexual function, energy levels, concentration, hair loss, and weight fluctuation.

These common symptoms actually aren’t so surprising given the possible relationship between the hypothyroidism and Low T.

Thyroid and Low Testosterone — The Cause

When examining the distinct relationship between the thyroid and low testosterone, researchers have observed a chain reaction that can take place starting in the thyroid gland.

Proper production of thyroid hormone stimulates the hypothalamus, resulting in production of GnRH (gonadotropin-releasing hormone).

GnRH then signals the pituitary gland to produce LH (luteinizing hormone).

LH signals the testes to produce — you guessed it — testosterone.

If this system starts off with poor production of thyroid hormone (hypothyroidism), a normal level of GnRH won’t be produced, the pituitary gland then won’t get the proper message, causing low production of LH. Poor LH production means the testes won’t be signalled to produce enough testosterone.

The final result? You can be left with Low T levels.

It might also interest you to note that studies show a connection between hyperthyroidism and testosterone levels as well.

Thyroid and Low Testosterone — Some Treatment Options

This is where it gets complicated — we noted above the overlapping symptoms.

When dealing with your hormone levels, we’re looking at a very complicated system, so diagnoses and treatments are always complex.

We need to get an overall picture of what is going on through a complete panel of tests.

Learn more about how treatment for hypothyroidism in men works here


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(Augie) Juan Augustine Galindo Jr. MPAS, PA-C

(Augie) Juan Augustine Galindo Jr. MPAS, PA-C started his career in healthcare as a fireman/paramedic in West Texas where he served on the Midland Fire Department from 1998-2004.   He became interested in testosterone treatment after seeing how hormone replacement doctors helped those suffering from low testosterone.   After graduating from the Texas Tech Health Sciences Center Physician Assistant Program, he moved to DFW where he currently lives with his wife and three children.


  1. Kevin Soave on 02/22/2022 at 7:39 am

    HELP !! I’m stuck up here in Michigan, my thyroid is sorta whacked, Doc even said so- but went ahead and put pellets in my ass for estradiol and testosterone- Nothing for thyroid- other than mentioning its not right- Have any resources up here in Michigan.

    • Hello Mr. Soave,

      I am sorry to hear about your struggles. Unfortunately, I do not have any contacts in Michigan. I can tell you that I personally struggled with both Low T and hypothyroidism. I did not feel right when I started TRT until I adequately addressed my thyroid issues. I offer pellets to our patients, but I consider injections to be a superior treatment method. It may take some digging, but I encourage you to find a local provider who won’t ignore your thyroid while only treating your testosterone levels.

      Best regards,

      Augie Galindo MPAS, PA-C
      Testosterone Centers of Texas | Managing Partner

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