TRT and Your Urinary and Sexual Health—Research Shows Benefits

The importance of testosterone in men’s overall health is well known.

This hormone plays a crucial role in many bodily systems that include:

  • Sexual function
  • Urinary health
  • Fat metabolism
  • Lean muscle production
  • Bone mass development and maintenance
  • Energy production

When your testosterone levels fall below normal, these systems may begin to function poorly, which can lead to the symptoms of hypogonadism (the medical term for low testosterone) such as:

  • Fatigue
  • Decreased sexual arousal
  • Low mood
  • Increased risk of diabetes

Learn the facts about low testosterone in our comprehensive guide.

A man smiles while holding a newborn baby. Many men have questions about TRT and fertility.

Studies Show Improved Quality of Life Through TRT

Researchers from the Boston University School of Medicine (BUSM) and the Boston University School of Public Health (BUSPH) in cooperation with urologists in Germany studied the effects of long-term Testosterone Replacement Therapy (TRT) on urinary health, sexual function, and overall quality of life in men with clinically diagnosed, symptomatic hypogonadism.

Research Methods

More than 656 men in their 50’s and 60’s who had total testosterone levels of 349 ng/dL (12.1 nmol/l) or less with identifiable symptoms of low testosterone participated in the observational research project.

The group receiving TRT comprised 360 men who had received 1,000 mg of supplemental testosterone per 12 weeks for up to 10 years, while the 296 men who had elected to forgo TRT made up the control group.

82 patients from each group were matched according to age, waist circumference, and body mass index (BMI), resulting in 82 matched pairs that totalled 164 men.

Data was collected, analyzed, and adjusted for estimated differences in components of metabolic syndrome and quality of life.

Learn more about the research study here.

The Surprising Results

The researchers expected the study to show an increase in prostate size that contributed to worsened lower urinary tract difficulties.

However, the group receiving TRT found significant improvements in urinary function, such as:

  • Less-frequent urination
  • More complete emptying of the bladder
  • Strengthened urinary stream
  • Fewer instances of waking up at night to urinate

Patients receiving TRT also showed increased scores on assessments that measured their erectile/sexual health and general quality of life.

Even more promising, the improvements were maintained throughout the follow-up period.

The control group, who opted against receiving testosterone therapy, saw continued and even worsening urinary and sexual performance.

The Benefits of TRT—Learn More

Studies such as this one continue to provide evidence that Testosterone Replacement Therapy can relieve the debilitating symptoms of low testosterone and can increase your quality of life.

Ready to learn more?

We’ve written a comprehensive guide that provides facts and the answers to the most common questions concerning TRT and the treatment of low testosterone.

Read the Guide


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(Augie) Juan Augustine Galindo Jr. MPAS, PA-C

(Augie) Juan Augustine Galindo Jr. MPAS, PA-C started his career in healthcare as a fireman/paramedic in West Texas where he served on the Midland Fire Department from 1998-2004.   He became interested in testosterone treatment after seeing how hormone replacement doctors helped those suffering from low testosterone.   After graduating from the Texas Tech Health Sciences Center Physician Assistant Program, he moved to DFW where he currently lives with his wife and three children.

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