Depression and Low Testosterone—Could There Be a Treatment Overlap?

The connection between depression and low testosterone could be what's on the mind of this middle-aged business man, who is wearing a gray suit and sitting in front of a laptop computer with his head resting in his hands.

Depression has been a major health concern for decades. According to the Anxiety and Depression Association of America (ADAA), this energy- and vitality-draining condition adversely affects more than 16.1 million American adults per year—roughly 7% of the U.S. population. Major depressive disorder is also the leading cause of disability among working-age individuals in the nation.…

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Slowing the Premature Aging Process—TRT and Improved Muscle Performance in Older Men

Man in red sweater rubs the bridge of his nose. He may be experiencing premature aging. Research shows TRT may benefit men like him.

The likelihood of discovering low testosterone increases as men get older. As a result of this treatable condition, men often notice a significant reduction in their energy levels, muscle mass, muscle strength, and quality of life earlier in life than expected. This premature aging and frailty often affects balance and how quickly the muscles fatigue,…

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Research Supports TRT for Men With Low-T-Related Obesity

Female medical assistant measures the waist of a male patient. Research shows TRT may benefit obese patients.

“Men with hypogonadism and obesity receiving long-term testosterone therapy achieved progressive and sustained weight loss, while untreated controls gained,” said Karim Haider, MD, a urologist, andrologist, and researcher, who presented his research findings at ENDO 2019, the Endocrine Society’s annual conference. Although we have previously highlighted research showing that low testosterone contributes to obesity, this…

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Testosterone Pellets: Research Casts Doubt on Marketing Claims

A male scientist in a white lab coat looks down into a microscope while researching the benefits and disadvantages of testosterone pellets.

The concept underlying testosterone pellets is a simple one—implant the time-release medication under the skin, and let your body do the rest. For busy patients hoping to find relief for the symptoms of chronic low testosterone through Testosterone Replacement Therapy (TRT), an implant-and-forget approach can sound quite attractive when compared to other methods of treatment.…

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Low Testosterone and Comorbidity: Research Links Low T to Poor Health

Male researcher looks into a microscope, possibly studying the link between low testosterone and comorbidity.

While most people associate testosterone with certain “male” behavioral characteristics like aggression and risk taking, testosterone actually plays a much more valuable role in human health by fueling and triggering a number of critical bodily systems, including: Producing of lean muscle mass Developing and maintaining bone tissue Regulating and distributing body fat Governing libido (sex…

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Male Pattern Baldness and Testosterone—Connection, Not Cause

A middle-aged man checks his hairline in the bathroom mirror. He may be concerned about the connection between baldness and testosterone.

Many men who seek treatment for the chronic symptoms of low testosterone are rightly concerned about possible side effects. However, many of these concerns are based on rumors, such as the incorrect assertion that testosterone causes male pattern baldness. This myth has been repeated for decades despite being based on very shaky information. In fact, there’s no…

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TRT and Your Urinary and Sexual Health—Research Shows Benefits

A man smiles while holding a newborn baby. Many men have questions about TRT and fertility.

The importance of testosterone in men’s overall health is well known. This hormone plays a crucial role in many bodily systems that include: Sexual function Urinary health Fat metabolism Lean muscle production Bone mass development and maintenance Energy production When your testosterone levels fall below normal, these systems may begin to function poorly, which can…

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TRT and Blood Clots—Research Shows No Direct Connection

A doctor measures the blood pressure of a male patient. There is no evidence linking TRT to blood clotting events, but preventative monitoring represents best practices.

Patients seeking treatment for chronic low testosterone often express concern about a potential link between Testosterone Replacement Therapy (TRT) and increased blood pressure and blood clotting that could lead to heart attacks or strokes. Although an understandable concern, it’s important to understand the facts about how testosterone affects the viscosity (thickness) of a patient’s blood…

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TRT and Cardiovascular Disease: International Panel Finds Benefits Instead of Increased Risks

A young man wearing protective eye glasses works at a microscope, possibly researching a connection between TRT and cardiovascular disease.

Poorly-researched claims of a dangerous increase in cardiovascular disease (CVD) associated with Testosterone Replacement Therapy (TRT) have been circulated by the popular health media over the years. Reliable scientific studies reviewed by international experts fail to support the hysteria. In fact, the most reliable research available leans toward Low Testosterone, not TRT, as a likely…

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